Eytan Ruppin Selected Research

Aspartate Carbamoyltransferase

1/2018	Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures.
11/2015	Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis.

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Eytan Ruppin Research Topics

Disease

63	Neoplasms (Cancer) 06/2022 - 06/2009
14	COVID-19 06/2022 - 01/2020
14	Melanoma (Melanoma, Malignant) 01/2022 - 07/2018
10	Breast Neoplasms (Breast Cancer) 01/2021 - 06/2009
7	Infections 04/2022 - 12/2018
5	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2019
5	Carcinogenesis 12/2020 - 02/2013
3	Lung Neoplasms (Lung Cancer) 01/2021 - 10/2020
3	Glioblastoma (Glioblastoma Multiforme) 06/2018 - 12/2015
2	Disease Progression 06/2022 - 01/2021
2	Pulmonary Hypertension 06/2022 - 01/2022
2	Rectal Neoplasms (Rectal Cancer) 01/2022 - 01/2020
2	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 12/2017
2	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 01/2016
2	Triple Negative Breast Neoplasms 01/2021 - 10/2020
2	Pancreatic Neoplasms (Pancreatic Cancer) 12/2019 - 12/2010
2	Metabolic Diseases (Metabolic Disease) 12/2018 - 09/2008
2	Alzheimer Disease (Alzheimer's Disease) 01/2017 - 01/2014
2	Drug-Related Side Effects and Adverse Reactions 03/2016 - 02/2012
1	Anemia 04/2022
1	Turcot syndrome 01/2022
1	Neutropenia 12/2021
1	Hyperferritinemia 12/2021
1	Hyperbilirubinemia 12/2021
1	Cytokine Release Syndrome 12/2021
1	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 12/2021
1	Hypertriglyceridemia 12/2021
1	Liver Neoplasms (Liver Cancer) 11/2021
1	Cholangiocarcinoma 11/2021
1	Communicable Diseases (Infectious Diseases) 10/2021
1	Inflammation (Inflammations) 10/2021
1	Neural crest tumor 01/2021

Drug/Important Bio-Agent (IBA)

13	Pharmaceutical PreparationsIBA 05/2022 - 06/2011
9	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2009
9	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2009
8	Immune Checkpoint InhibitorsIBA 01/2022 - 10/2018
8	EnzymesIBA 11/2019 - 09/2008
6	mRNA VaccinesIBA 06/2022 - 08/2021
6	BNT162 VaccineIBA 06/2022 - 08/2021
6	VaccinesIBA 06/2022 - 08/2021
6	Messenger RNA (mRNA)IBA 04/2022 - 12/2018
5	RNA (Ribonucleic Acid)IBA 05/2022 - 01/2017
4	Transcription Factors (Transcription Factor)IBA 01/2022 - 12/2010
4	Glutamine (L-Glutamine)FDA Link 01/2019 - 03/2011
3	Antiviral Agents (Antivirals)IBA 06/2022 - 09/2021
3	MicroRNAs (MicroRNA)IBA 01/2021 - 06/2009
3	Serine (L-Serine)FDA Link 01/2021 - 11/2012
3	Amino Acids FDA Link 12/2019 - 03/2011
3	pyrimidineIBA 01/2019 - 11/2015
3	ProteomeIBA 12/2018 - 01/2016
3	Small Interfering RNA (siRNA)IBA 07/2018 - 09/2015
2	Hemoglobins (Hemoglobin)IBA 06/2022 - 01/2022
2	CholesterolIBA 04/2022 - 03/2015
2	Peptides (Polypeptides)IBA 01/2022 - 01/2021
2	LigandsIBA 01/2022 - 11/2019
2	Immunoglobulin G (IgG)IBA 12/2021 - 08/2021
2	AntibodiesIBA 12/2021 - 08/2021
2	DNA (Deoxyribonucleic Acid)IBA 11/2021 - 07/2009
2	Rosuvastatin Calcium (Crestor)FDA Link 03/2021 - 01/2021
2	UbiquinoneIBA 03/2021 - 01/2021
2	Vitamin D FDA LinkGeneric 03/2021 - 01/2021
2	Flecainide (Tambocor)FDA LinkGeneric 03/2021 - 01/2021
2	Ezetimibe (Zetia)FDA Link 03/2021 - 01/2021
2	UbiquitinIBA 01/2021 - 12/2020
2	Ligases (Synthetase)IBA 01/2021 - 12/2020
2	3' Untranslated Regions (3' UTR)IBA 01/2021 - 12/2018
2	LipidsIBA 10/2020 - 11/2012
2	Argininosuccinate Synthase (Argininosuccinate Synthetase)IBA 01/2020 - 01/2019
2	AntigensIBA 01/2020 - 11/2018
2	HLA Antigens (Human Leukocyte Antigens)IBA 01/2020 - 11/2018
2	Glutathione (Reduced Glutathione)IBA 01/2020 - 01/2019
2	TOR Serine-Threonine KinasesIBA 12/2019 - 11/2015
2	Phosphotransferases (Kinase)IBA 12/2019 - 01/2012
2	Aspartic Acid (Aspartate)FDA Link 01/2019 - 11/2015
2	Carbamyl Phosphate (Carbamoyl Phosphate)IBA 01/2018 - 11/2015
2	Aspartate CarbamoyltransferaseIBA 01/2018 - 11/2015
2	NitrogenIBA 01/2018 - 11/2015
2	Tricarboxylic AcidsIBA 12/2015 - 01/2015
2	FumaratesIBA 01/2015 - 08/2011
2	Adenosine Triphosphate (ATP)IBA 08/2014 - 03/2011
1	Complement C3 (C3 Complement)IBA 04/2022
1	Drug CombinationsIBA 01/2022
1	Complex MixturesIBA 01/2022
1	pembrolizumabIBA 01/2022
1	Immunologic Factors (Immunomodulators)IBA 01/2022
1	Programmed Cell Death 1 ReceptorIBA 01/2022
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 12/2021
1	Chimeric Antigen ReceptorsIBA 12/2021
1	CytokinesIBA 10/2021
1	Cysteine (L-Cysteine)FDA Link 01/2021
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2021
1	16S Ribosomal RNAIBA 01/2021
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2021
1	Untranslated RNA (Noncoding RNA)IBA 01/2021
1	Poly AIBA 01/2021

Therapy/Procedure

27	Therapeutics 01/2022 - 06/2011
11	Immunotherapy 01/2022 - 01/2018
2	Chemoradiotherapy 01/2022 - 01/2020
2	Injections 11/2021 - 01/2017
1	Neoadjuvant Therapy 01/2022